Recombinant CEA antibody (full length)

Catalog No. ABIN7877816

This Rabbit Monoclonal antibody specifically detects CEA in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant CEA antibody (full length) (ABIN7877816)

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CEA antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: C66-6470R

Product Details anti-CEA Antibody

Binding Specificity: full length

Purpose: Recombinant Carcinoembryonic Antigen Antibody / CEA

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human CEA protein was used as the immunogen for the recombinant Carcinoembryonic Antigen antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant Carcinoembryonic Antigen antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant Carcinoembryonic Antigen antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CEA

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Alternative Name: Carcinoembryonic Antigen

Background: This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

UniProt: P06731