CD44 antibody (full length)

Catalog No. ABIN7877891

This Mouse Monoclonal antibody specifically detects CD44 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for CD44 antibody (full length) (ABIN7877891)

Target: CD44

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD44 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: HCAM-6779

Product Details anti-CD44 Antibody

Binding Specificity: full length

Purpose: CD44 Antibody / H-CAM (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human CD44 protein was used as the immunogen for the CD44 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the CD44 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the CD44 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD44

Target: CD44

Alternative Name: CD44

Background: This antibody recognizes an epitope encoded by exon v3 on the variant portion of human CD44. The CD44 Molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA.The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling