CD7 antibody (full length)

Catalog No. ABIN7877947

The Mouse Monoclonal anti-CD7 antibody (Clone CD7-3737) (ABIN7877947) specifically detects CD7 in ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for CD7 antibody (full length) (ABIN7877947)

Target: CD7

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CD7-3737

Product Details anti-CD7 Antibody

Binding Specificity: full length

Purpose: CD7 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A recombinant human full-length CD7 protein was used as the immunogen for this CD7 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the CD7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the CD7 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD7

Target: CD7

Alternative Name: CD7

Background: Recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

UniProt: P09564

Pathways: Cell-Cell Junction Organization