CD7 antibody (full length)

Catalog No. ABIN7877948

This Mouse Monoclonal antibody specifically detects CD7 in ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CD7 antibody (full length) (ABIN7877948)

Target: CD7

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CD7-3737

Product Details anti-CD7 Antibody

Binding Specificity: full length

Purpose: CD7 Antibody

Purification: Protein G affinity chromatography

Immunogen: A recombinant human full-length CD7 protein was used as the immunogen for this CD7 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the CD7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CD7 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD7

Target: CD7

Alternative Name: CD7

Background: Recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

UniProt: P09564

Pathways: Cell-Cell Junction Organization