Recombinant CD81 antibody (full length)

Catalog No. ABIN7877953

The Mouse Monoclonal anti-CD81 antibody (Clone rC81-3442) (ABIN7877953) specifically detects CD81 in FACS, WB, IF, Func and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant CD81 antibody (full length) (ABIN7877953)

Target: CD81

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD81 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RC81-3442

Product Details anti-CD81 Antibody

Binding Specificity: full length

Purpose: Recombinant CD81 Antibody

Purification: Protein G affinity chromatography

Immunogen: Recombinant full-length human CD81 protein was used as the immunogen for the recombinant CD81 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant CD81 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant CD811 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD81

Target: CD81

Alternative Name: CD81

Background: Recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C