CHID1 antibody (full length)

Catalog No. ABIN7877976

The Mouse Monoclonal anti-CHID1 antibody is suitable to detect CHID1 in samples from Human. It has been validated for IHC (p).

Quick Overview for CHID1 antibody (full length) (ABIN7877976)

Target: CHID1 (Chitinase Domain Containing 1 (CHID1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CHID1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CHID1-6368

Product Details anti-CHID1 Antibody

Binding Specificity: full length

Purpose: SI-CLP Antibody / CHID1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human SI-CLP protein was used as the immunogen for the CHID1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the SI-CLP antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the SI-CLP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CHID1

Target: CHID1 (Chitinase Domain Containing 1 (CHID1))

Alternative Name: SI-CLP

Background: SI-CLP (stabilin-1 interacting chitinase-like), also known as CHID1 (chitinase domain-containing protein 1), is a 393 amino acid secreted protein that belongs to the glycosyl hydrolase 18 family. SI-CLP interacts with STAB1 and localizes to lysosome in cells of monocytic, T, B and epithelial origin. SI-CLP is a saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro). The SI-CLP protein is up-regulated by IL4/interleukin-4 and dexamethasone in the macrophages, and is also up-regulated by glucocorticoid. Existing as three alternatively spliced isoforms, the SI-CLP gene is conserved in chimpanzee, canine, bovine, mouse, rat, chicken, zebrafish, fruit fly, mosquito, A. thaliana and rice, and maps to human chromosome 11p15.5.

UniProt: Q9BWS9