Decorin antibody (full length)

Catalog No. ABIN7878126

The Mouse Monoclonal anti-Decorin antibody is suitable to detect Decorin in samples from Human. It has been validated for WB, IHC (p), IF and FACS.

Quick Overview for Decorin antibody (full length) (ABIN7878126)

Target: Decorin (DCN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Decorin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Grade: Carrier-free

Clone: DCN-6289

Product Details anti-Decorin Antibody

Binding Specificity: full length

Purpose: Decorin Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length protein was used as the immunogen for the Decorin antibody.

Isotype: IgG1, lambda

Application Details

Application Notes: Optimal dilution of the Decorin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Decorin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Decorin

Target: Decorin (DCN)

Alternative Name: Decorin

Background: Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation, flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I, II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors, intercellular matrix molecules, such as Fibronectin and Thrombospondin, and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGF may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. For immunostaining, pre-incubation with chondroitinase-SBC or testicular hyaluronidase may be required to expose the epitope.

UniProt: P07585

Pathways: Glycosaminoglycan Metabolic Process