Elastin antibody (full length)

Catalog No. ABIN7878161

This Mouse Monoclonal antibody specifically detects Elastin in ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Elastin antibody (full length) (ABIN7878161)

Target: Elastin (ELN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Elastin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ELN-2069

Product Details anti-Elastin Antibody

Binding Specificity: full length

Purpose: Elastin Antibody

Purification: Protein G affinity chromatography

Immunogen: Recombinant full-length human Elastin protein was used as the immunogen for the Elastin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Elastin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Elastin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Elastin

Target: Elastin (ELN)

Alternative Name: Elastin

Background: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries.It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticityto the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

UniProt: P15502

Pathways: Regulation of Actin Filament Polymerization