EIF4A2 antibody (full length)

Catalog No. ABIN7878209

This Mouse Monoclonal antibody specifically detects EIF4A2 in ELISA. It exhibits reactivity toward Human.

Quick Overview for EIF4A2 antibody (full length) (ABIN7878209)

Target: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EIF4A2 antibody is un-conjugated

Application: ELISA

Grade: Carrier-free

Clone: PCRP-EIF4A2-2B5

Product Details anti-EIF4A2 Antibody

Binding Specificity: full length

Purpose: EIF4A2 Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human EIF4A2 protein was used as the immunogen for the EIF4A2 antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the EIF4A2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the EIF4A2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for EIF4A2

Target: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Alternative Name: EIF4A2

Background: Translation initiation in eukaryotes necessitates the assembly of an 80S ribosomal complex. Eukaryotic initiation factors (eIFs) are utilized in a sequence of reactions that leads to 80S ribosomal assembly and initiation of translation. Mammalian eukaryotic translation initiation factor 4F (eIF4F) is a protein complex that contains eIF4A, eIF4E and eIF4G, binds mRNA at a5 cap, eIF4A (I, II) are bidirectional RNA helicases, and eIF4G (I, II) are scaffolding proteins which coordinate eIF4E, eIF4A, eIF3and the 40S ribosome. Human eIF4AI (eIF4A, DDX2A) is a 406 amino acid protein that is 92.7 % homologous to mouse eIF4AI. The promoter region of human eIF4A1 contains TATA and CAAT motifs and consensus binding sites to Sp1 and AP2.

UniProt: Q14240