Recombinant FOXL2 antibody (full length)

Catalog No. ABIN7878250

The Rabbit Monoclonal anti-FOXL2 antibody (Clone FOXL2-8362R) (ABIN7878250) specifically detects FOXL2 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant FOXL2 antibody (full length) (ABIN7878250)

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FOXL2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FOXL2-8362R

Product Details anti-FOXL2 Antibody

Binding Specificity: full length

Purpose: Forkhead box protein L2 Antibody / FOXL2

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human FOXL2 protein was used as the immunogen for the FOXL2 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the FOXL2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the FOXL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FOXL2

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Alternative Name: Forkhead box protein L2

Background: FOXL2 is a critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. It prevents trans-differentiation of ovary to testis through transcriptional repression of the sertoli cell-promoting gene SOX9. FOXL2 is mainly expressed in ovary, parathyroid gland and sex cord-stromal tumors. FOXL2 is generally used for diagnosis of sex cord-stromal tumors with Inhibin, Calretinin and SF-1.

UniProt: P58012

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity