FOSL2 antibody (full length)

Catalog No. ABIN7878254

This Mouse Monoclonal antibody specifically detects FOSL2 in FACS and IF. It exhibits reactivity toward Human.

Quick Overview for FOSL2 antibody (full length) (ABIN7878254)

Target: FOSL2 (FOS-Like Antigen 2 (FOSL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOSL2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Grade: Carrier-free

Clone: PCRP-FOSL2-1B1

Product Details anti-FOSL2 Antibody

Binding Specificity: full length

Purpose: FRA2 Antibody / FOSL2 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human FOSL2 protein was used as the immunogen for the FRA2 antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the FRA2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the FRA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FOSL2

Target: FOSL2 (FOS-Like Antigen 2 (FOSL2))

Alternative Name: FRA2

Background: The Fos related gene, Fra-2, was initially molecularly cloned from chicken genomic DNA and shown to represent a new member of the immediate early gene family. The human counterpart of the chicken Fra-2 gene has since been described. Sequence alignment shows that the amino acid sequences conserved among Fra-2, c-Fos, Fra-1 and Fos B are contained in five regions. Region 2, the longest and most highly conserved region, contains the leucine zipper structure and the basic region, suggesting that like Fos, Fra-1 and Fos B, Fra-2 also forms heterodimers with c-Jun that recognize a specific DNA sequence such as the binding site for transcription factor AP-1. Such a model is further supported by the finding that the Fra-2 gene product forms a complex with c-Jun in growth-stimulated cells

UniProt: P15408

Pathways: Feeding Behaviour, Photoperiodism