FOSL2 antibody (full length)

Catalog No. ABIN7878255

The Mouse Monoclonal anti-FOSL2 antibody is suitable to detect FOSL2 in samples from Human. It has been validated for FACS and IF.

Quick Overview for FOSL2 antibody (full length) (ABIN7878255)

Target: FOSL2 (FOS-Like Antigen 2 (FOSL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOSL2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: PCRP-FOSL2-1B1

Product Details anti-FOSL2 Antibody

Binding Specificity: full length

Purpose: FRA2 Antibody / FOSL2

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human FOSL2 protein was used as the immunogen for the FRA2 antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the FRA2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the FRA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FOSL2

Target: FOSL2 (FOS-Like Antigen 2 (FOSL2))

Alternative Name: FRA2

Background: The Fos related gene, Fra-2, was initially molecularly cloned from chicken genomic DNA and shown to represent a new member of the immediate early gene family. The human counterpart of the chicken Fra-2 gene has since been described. Sequence alignment shows that the amino acid sequences conserved among Fra-2, c-Fos, Fra-1 and Fos B are contained in five regions. Region 2, the longest and most highly conserved region, contains the leucine zipper structure and the basic region, suggesting that like Fos, Fra-1 and Fos B, Fra-2 also forms heterodimers with c-Jun that recognize a specific DNA sequence such as the binding site for transcription factor AP-1. Such a model is further supported by the finding that the Fra-2 gene product forms a complex with c-Jun in growth-stimulated cells

UniProt: P15408

Pathways: Feeding Behaviour, Photoperiodism