GTF2B antibody (full length)

Catalog No. ABIN7878279

The Mouse Monoclonal anti-GTF2B antibody is suitable to detect GTF2B in samples from Human. It has been validated for ELISA and FACS.

Quick Overview for GTF2B antibody (full length) (ABIN7878279)

Target: GTF2B (General Transcription Factor IIB (GTF2B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GTF2B antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: PCRP-GTF2B-1D1

Product Details anti-GTF2B Antibody

Binding Specificity: full length

Purpose: TFIIB Antibody / GTF2B

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the TFIIB antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the TFIIB antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TFIIB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for GTF2B

Target: GTF2B (General Transcription Factor IIB (GTF2B))

Alternative Name: TFIIB

Background: In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH, and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. Template commitment is established by the initial binding of TFIID to the TATA element of the promotor, a step which may be facilitated by TFIIA. TFIIB then acts as the bridge between TFIID and RNA polymerase II.

UniProt: Q00403