GCLM antibody (full length)

Catalog No. ABIN7878297

The Mouse Monoclonal anti-GCLM antibody is suitable to detect GCLM in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for GCLM antibody (full length) (ABIN7878297)

Target: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GCLM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CPTC-GCLM-1

Product Details anti-GCLM Antibody

Binding Specificity: full length

Purpose: GCLM Antibody

Purification: Protein G affinity chromatography

Immunogen: Recombinant human full-length GCLM protein was used as the immunogen for the GCLM antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the GCLM antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the GCLM antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for GCLM

Target: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Alternative Name: GCLM

Background: GCLM, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.

UniProt: P48507