Recombinant CGA antibody (full length)

Catalog No. ABIN7878309

The Rabbit Monoclonal anti-CGA antibody is suitable to detect CGA in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant CGA antibody (full length) (ABIN7878309)

Target: CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CGA antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CHGA-8929R

Product Details anti-CGA Antibody

Binding Specificity: full length

Purpose: CGA Antibody / CHGA / Chromogranin A

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the CGA antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the CGA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CGA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CGA

Target: CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))

Alternative Name: CGA

Background: Chromogranin A (CGA) is an acidic protein which is reported to be widely expressed in neural tissues and in secretory granules of human endocrine cells e.g. parathyroid gland, adrenal medulla, anterior pituitary gland, islet cells of the pancreas and C cells of the thyroid.GA is found in the large majority of epithelial NE tumors: pituitary adenomas, parathyroid and pancreatic islet cell tumors, medullary thyroid carcinoma, and carcinoid tumors.Together with synaptophysin, CGA is the most important marker for the identification of NE and neuronal tumors and NE/neuronal differentiation in other tumors.

UniProt: P10645

Pathways: Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport, Peptide Hormone Metabolism