GTF2IRD2 antibody (full length)

Catalog No. ABIN7878333

The Mouse Monoclonal anti-GTF2IRD2 antibody is suitable to detect GTF2IRD2 in samples from Human. It has been validated for WB and FACS.

Quick Overview for GTF2IRD2 antibody (full length) (ABIN7878333)

Target: GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GTF2IRD2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: PCRP-GTF2IRD2-1B4

Product Details anti-GTF2IRD2 Antibody

Binding Specificity: full length

Purpose: GTF2IRD2 Antibody / GTF2IRD2 alpha

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human General transcription factor II-I repeat domain-containing protein 2A protein was used as the immunogen for the GTF2IRD2 antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the GTF2IRD2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the GTF2IRD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for GTF2IRD2

Target: GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))

Alternative Name: GTF2IRD2

Background: The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (also called GTF2IRD2 alpha and GTF2IRD2A) and GTF2IRD2B. Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits including facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities.

UniProt: Q86UP8