IGFBP3 antibody (full length)

Catalog No. ABIN7878418

The Mouse Monoclonal anti-IGFBP3 antibody (Clone IGFBP3-3517) (ABIN7878418) specifically detects IGFBP3 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for IGFBP3 antibody (full length) (ABIN7878418)

Target: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IGFBP3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IGFBP3-3517

Product Details anti-IGFBP3 Antibody

Binding Specificity: full length

Purpose: IGFBP3 Antibody

Purification: Protein A/G affinity

Immunogen: Recombinant human full-length IGFBP3 protein was used as the immunogen for the IGFBP3 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the IGFBP3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the IGFBP3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for IGFBP3

Target: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Alternative Name: IGFBP3

Background: The Insulin-like growth factor-binding proteins, or IGFBPs, are a family of homologous proteins that have co-evolved with the IGFs. They serve not only as shuttle molecules for the soluble IGFs, but also confer a level of regulation to the IGF signaling system. IGFBP3 is the most abundant IGFBP and is complexed with roughly 80 % of the serum IGFs.

UniProt: P17936

Pathways: Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding