Recombinant Cytokeratin 1 antibody (full length)

Catalog No. ABIN7878473

This Rabbit Monoclonal antibody specifically detects Cytokeratin 1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant Cytokeratin 1 antibody (full length) (ABIN7878473)

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Cytokeratin 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KRT1-8342R

Product Details anti-Cytokeratin 1 Antibody

Binding Specificity: full length

Purpose: Cytokeratin 1 Antibody / CK1 / KRT1

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the Cytokeratin 1 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the Cytokeratin 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Cytokeratin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Cytokeratin 1

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Alternative Name: Cytokeratin 1

Background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis.

UniProt: P04264