Recombinant KRT15 antibody (full length)

Catalog No. ABIN7878483

The Rabbit Monoclonal anti-KRT15 antibody is suitable to detect KRT15 in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant KRT15 antibody (full length) (ABIN7878483)

Target: KRT15 (Keratin 15 (KRT15))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This KRT15 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KRT15-8312R

Product Details anti-KRT15 Antibody

Binding Specificity: full length

Purpose: Cytokeratin 15 Antibody / KRT15

Purification: Protein A affinity

Immunogen: Recombinant human full-length KRT15 protein was used as the immunogen for the Cytokeratin 15 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the Cytokeratin 15 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Cytokeratin 15 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for KRT15

Target: KRT15 (Keratin 15 (KRT15))

Alternative Name: Cytokeratin 15

Background: Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. KRT15 is downregulated in activated keratinocytes. It is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.

UniProt: P19012