Recombinant LHB antibody (full length)

Catalog No. ABIN7878539

This Mouse Monoclonal antibody specifically detects LHB in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant LHB antibody (full length) (ABIN7878539)

Target: LHB (Luteinizing Hormone beta Polypeptide (LHB))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LHB antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RLHb-1613

Product Details anti-LHB Antibody

Binding Specificity: full length

Purpose: LH beta Antibody / Luteinizing Hormone beta

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the LH beta antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the LH beta antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the LH beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for LHB

Target: LHB (Luteinizing Hormone beta Polypeptide (LHB))

Alternative Name: LH beta

Target Type: Hormone

Background: LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor, however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

UniProt: P01229

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process