MEF2D antibody (full length)

Catalog No. ABIN7878687

The Mouse Monoclonal anti-MEF2D antibody is suitable to detect MEF2D in samples from Human. It has been validated for IHC (p), FACS and IF.

Quick Overview for MEF2D antibody (full length) (ABIN7878687)

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MEF2D antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Grade: Carrier-free

Clone: PCRP-MEF2D-3A4

Product Details anti-MEF2D Antibody

Binding Specificity: full length

Purpose: MEF2D Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human MEF2D protein was used as the immunogen for the MEF2D antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the MEF2D antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the MEF2D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MEF2D

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Alternative Name: MEF2D

Background: The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each duing embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5 and MRF4, are one class of identified factors. A second family of DNA-binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF-2) family. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.

UniProt: Q14814