NME2 antibody (full length)

Catalog No. ABIN7878750

The Mouse Monoclonal anti-NME2 antibody is suitable to detect NME2 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for NME2 antibody (full length) (ABIN7878750)

Target: NME2 (Nucleoside diphosphate kinase B (NME2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NME2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: NME2-6437

Product Details anti-NME2 Antibody

Binding Specificity: full length

Purpose: NDKB Antibody / Nucleoside diphosphate kinase B / NME2 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the NDKB antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the NDKB antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the NDKB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for NME2

Target: NME2 (Nucleoside diphosphate kinase B (NME2))

Alternative Name: NDKB

Background: The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.

UniProt: P22392