PDLIM1 antibody (full length)

Catalog No. ABIN7878783

The Mouse Monoclonal anti-PDLIM1 antibody is suitable to detect PDLIM1 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for PDLIM1 antibody (full length) (ABIN7878783)

Target: PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDLIM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CPTC-PDLIM1-1

Product Details anti-PDLIM1 Antibody

Binding Specificity: full length

Purpose: PDLIM1 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A recombinant human full-length PDLIM1 protein was used as the immunogen for this PDLIM1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the PDLIM1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the PDLIM1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for PDLIM1

Target: PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))

Alternative Name: PDLIM1

Background: CLP36, also known as PDLIM1, CLIM1 or Elfin, is a 329 amino acid cytoplasmic protein that associates with actin stress fibers at the cytoskeleton. Expressed at high levels in skeletal muscle and heart and at lower levels in colon, small intestine, spleen, lung, placenta, kidney, liver, thymus and pancreas, CLP36 functions as a cytoskeletal protein that is thought to act as an adaptor, bringing target proteins to the cytoskeleton. Specifically, CLP36 interacts with Clik1 (-actinin-1, thereby facilitating the association of Clik1 with actin stress fibers. CLP36 contains one PDZ domain and one LIM zinc-binding domain through which it conveys its protein-protein binding capabilities. Human CLP36 shares 88 % sequence similarity with its rat counterpart, suggesting a conserved function between species.

UniProt: O00151