POGZ antibody (full length)

Catalog No. ABIN7878822

The Mouse Monoclonal anti-POGZ antibody is suitable to detect POGZ in samples from Human. It has been validated for FACS.

Quick Overview for POGZ antibody (full length) (ABIN7878822)

Target: POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This POGZ antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: PCRP-POGZ-1B2

Product Details anti-POGZ Antibody

Binding Specificity: full length

Purpose: POGZ Antibody / Pogo transposable element with ZNF domain

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human Pogo transposable element with ZNF domain protein was used as the immunogen for the POGZ antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the POGZ antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the POGZ antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for POGZ

Target: POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

Alternative Name: POGZ

Background: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

UniProt: Q7Z3K3