PRMT7 antibody (full length)

Catalog No. ABIN7878877

The Mouse Monoclonal anti-PRMT7 antibody (Clone PCRP-PRMT7-1A7) (ABIN7878877) specifically detects PRMT7 in IF and FACS. The antibody is reactive with Human samples.

Quick Overview for PRMT7 antibody (full length) (ABIN7878877)

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PRMT7 antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-PRMT7-1A7

Product Details anti-PRMT7 Antibody

Binding Specificity: full length

Purpose: PRMT7 Antibody

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human PRMT7 protein was used as the immunogen for the PRMT7 antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the PRMT7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PRMT7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PRMT7

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Alternative Name: PRMT7

Background: Arginine methylation is an irreversible protein modification catalyzed by Arginine methyltransferases, such as PRMT7, which uses S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport and RNA splicing. PRMT7 has two methyltransferase domains, each containing a putative AdoMet-binding motif. The N-terminal methyltransferase domain closely resembles the catalytic core of PRMT5, and the C-terminal domain is most similar to that of PRMT1. Three PRMT7 splice variants have been identified by database analysis. PRMT7 is localized to the nucleus and cytoplasm and moderate expression is observed in adult brain and lung tissues.

UniProt: Q9NVM4

Pathways: Ribonucleoprotein Complex Subunit Organization