LMYC antibody (full length)

Catalog No. ABIN7878881

This Mouse Monoclonal antibody specifically detects LMYC in WB, ELISA, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for LMYC antibody (full length) (ABIN7878881)

Target: LMYC (MYCL) (Protein L-Myc (MYCL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LMYC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-MYCL-2D5

Product Details anti-LMYC Antibody

Binding Specificity: full length

Purpose: L-Myc Antibody / MYCL1

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human MYCL protein was used as the immunogen for the L-Myc antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the L-Myc antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the L-Myc antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for LMYC

Target: LMYC (MYCL) (Protein L-Myc (MYCL))

Alternative Name: L-Myc

Background: Oncogene-encoded proteins c-Myc, N-Myc, and L-Myc function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors, the N-Myc gene in neuroblastomas, and the L-Myc gene in human small cell lung carcinomas. c-Myc protein is a transcription factor localized to the nucleus of the cell. It seems to be involved in activating the transcription of growth-related genes. c-Myc binds to DNA during transcription as a heterodimeric complex with Max. c-Myc is phosphorylated in vitro by p44/42 MAP kinase at Ser62 and in vivo at both Thr58 and Ser62. Mutation of Thr58 and Ser62 to Ala inhibits the ability of c-Myc to activate transcription.

UniProt: P12524

Pathways: Warburg Effect