Retinoid X Receptor gamma antibody (full length)

Catalog No. ABIN7878918

The Mouse Monoclonal anti-Retinoid X Receptor gamma antibody is suitable to detect Retinoid X Receptor gamma in samples from Human. It has been validated for ELISA and FACS.

Quick Overview for Retinoid X Receptor gamma antibody (full length) (ABIN7878918)

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoid X Receptor gamma antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Clone: PCRP-RXRG-5G6

Product Details anti-Retinoid X Receptor gamma Antibody

Binding Specificity: full length

Purpose: RXRG Antibody / RXR gamma (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the RXRG antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the RXRG antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the RXRG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Retinoid X Receptor gamma

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Alternative Name: RXRG

Background: Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARa, RARb and RARg, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXR, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.

UniProt: P48443

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway