Recombinant RPSA/Laminin Receptor antibody (full length)

Catalog No. ABIN7878925

The Rabbit Monoclonal anti-RPSA/Laminin Receptor antibody (Clone RPSA-6332R) (ABIN7878925) specifically detects RPSA/Laminin Receptor in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant RPSA/Laminin Receptor antibody (full length) (ABIN7878925)

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RPSA/Laminin Receptor antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RPSA-6332R

Product Details anti-RPSA/Laminin Receptor Antibody

Binding Specificity: full length

Purpose: 40S Ribosomal protein SA Antibody / RPSA / Laminin Receptor 1

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human RPSA protein was used as the immunogen for the 40S Ribosomal protein SA antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the 40S Ribosomal protein SA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the 40S Ribosomal protein SA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for RPSA/Laminin Receptor

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Alternative Name: 40S Ribosomal protein SA

Background: Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family member, 40S Ribosomal protein SA, also called Laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.

UniProt: P08865

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly