Recombinant RPSA/Laminin Receptor antibody (full length)

Catalog No. ABIN7878926

This Mouse Monoclonal antibody specifically detects RPSA/Laminin Receptor in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant RPSA/Laminin Receptor antibody (full length) (ABIN7878926)

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RPSA/Laminin Receptor antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: RRPSA-6333

Product Details anti-RPSA/Laminin Receptor Antibody

Binding Specificity: full length

Purpose: Recombinant RPSA Antibody / 40S Ribosomal protein SA / Laminin Receptor 1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human RPSA protein was used as the immunogen for the recombinant RPSA antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant RPSA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the recombinant RPSA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for RPSA/Laminin Receptor

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Alternative Name: RPSA

Background: Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.

UniProt: P08865

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly