SRF antibody (full length)

Catalog No. ABIN7879006

The Mouse Monoclonal anti-SRF antibody (Clone PCRP-SRF-1F1) (ABIN7879006) specifically detects SRF in WB, ELISA, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for SRF antibody (full length) (ABIN7879006)

Target: SRF (Serum Response Factor (SRF))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SRF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Grade: Carrier-free

Clone: PCRP-SRF-1F1

Product Details anti-SRF Antibody

Binding Specificity: full length

Purpose: SRF Antibody / Serum Response Factor (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human SRF protein was used as the immunogen for the SRF antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the SRF antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the SRF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SRF

Target: SRF (Serum Response Factor (SRF))

Alternative Name: SRF

Background: Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promotor elements in many muscle-specific promotors. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino-terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.

UniProt: P11831