TOM1L1
Reactivity: Human
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 488
Application Notes
Optimal dilution of the TOM1L1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.2 mg/mL
Buffer
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the TOM1L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
TOM1L1
(Target of Myb1 (Chicken)-Like 1 (TOM1L1))
Alternative Name
TOM1L1
Background
Tom1 (target of Myb 1) is a 492 amino acid cytoplasmic protein that belongs to the Tom1 family. Widely expressed with highest expression in heart, liver, placenta and skeletal muscle, Tom1 is thought to be involved in intracellular trafficking and may be associated with the translocation of ubiquitinated proteins to early endosomes for degradation. Tom1 contains one GAT domain and one VHS domain through which it interacts and complexes with proteins such as Tollip and endofin (also known as SARA). These interactions recruit Tom1 to the endosome, allowing it to participate in the endosomal trafficking of ubiquitin-tagged proteins.