TCF25 antibody (full length)

Catalog No. ABIN7879166

This Mouse Monoclonal antibody specifically detects TCF25 in WB. It exhibits reactivity toward Human.

Quick Overview for TCF25 antibody (full length) (ABIN7879166)

Target: TCF25 (Transcription Factor 25 (Basic Helix-Loop-Helix) (TCF25))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TCF25 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: PCRP-TCF25-1F12

Product Details anti-TCF25 Antibody

Binding Specificity: full length

Purpose: TCF-25 Antibody / Transcription factor 25

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human Transcription factor 25 protein was used as the immunogen for the TCF-25 antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the TCF-25 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TCF-25 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for TCF25

Target: TCF25 (Transcription Factor 25 (Basic Helix-Loop-Helix) (TCF25))

Alternative Name: TCF-25

Background: Nulp1 (nuclear localized protein 1), also known as TCF25 (transcription factor 25 (basic helix-loop-helix)), Hulp1 or FKSG26, is a 676 amino acid protein that plays a role in cell death. A member of the TCF25 family, Nulp1 utilizes its C-terminus to mediate transcriptional repression of SRF in vitro, and interacts with XIAP. Nulp1 localizes primarily to the nucleus but is also found in cytosol. Widely expressed, Nulp1 is found at high levels in embryonic brain and adult heart. The gene encoding Nulp1 maps to human chromosome 16q24.3, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn s disease, which is a gastrointestinal inflammatory condition.

UniProt: Q9BQ70