TGFB2 antibody (full length)

Catalog No. ABIN7879179

The Mouse Monoclonal anti-TGFB2 antibody is suitable to detect TGFB2 in samples from Human. It has been validated for IHC (p).

Quick Overview for TGFB2 antibody (full length) (ABIN7879179)

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TGFB2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: TGFB2-1679

Product Details anti-TGFB2 Antibody

Binding Specificity: full length

Purpose: TGF beta 2 Antibody / TGFB2 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the TGF beta 2 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the TGF beta 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the TGF beta 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for TGFB2

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Alternative Name: TGF beta 2

Background: Transforming growth factor Bs (TGFbs) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFa. It is now realized that TGFbs mediate many cell-cell interactions that occur during embryonic development. Three TGFbs have been identified in mammals. TGFb1, TGFb2 and TGFb3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFb requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFb3 protein has approximately 80 % identity to the mature region of both TGFb1 and TGFb2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity.

UniProt: P10600

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus