NUMA1 antibody (pSer395) (Cy5)
-
- Target See all NUMA1 Antibodies
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
-
Binding Specificity
- pSer395
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This NUMA1 antibody is conjugated to Cy5
-
Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Predicted Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human NuMA around the phosphorylation site of Ser395
- Isotype
- IgG
- Top Product
- Discover our top product NUMA1 Primary Antibody
-
-
- Application Notes
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
- Alternative Name
- NuMA (NUMA1 Products)
- Synonyms
- NUMA antibody, 6720401E04Rik antibody, AA764025 antibody, AL022610 antibody, AU014979 antibody, NUMA1 antibody, NuMA antibody, SP-H antibody, numa antibody, numa1 antibody, nuclear mitotic apparatus protein 1 antibody, nuclear mitotic apparatus protein 1 S homeolog antibody, NUMA1 antibody, Numa1 antibody, numa1 antibody, numa1.S antibody
- Background
-
Synonyms: NUMA 1, NuMA protein, NUMA1, SP H antigen, Structural nuclear protein, Centrophilin stabilizes mitotic spindle in mitotic cells, Nuclear mitotic apparatus protein 1, Nuclear mitotic apparatus protein.
Background: NuMA (Nuclear Mitotic Apparatus Protein) is an intranuclear protein and present in nucleus during interphase. At the onset of mitosis, it redistributes from the nucleus to two centrosomal structures that later will become part of the mitotic spindle pole. After anaphase, the protein redistributes from the spindle polar region into reforming nucleus. NuMA is an essential protein during mitosis for the terminal phases of chromosome separation and/or nuclear reassembly. Recently a study shows that NuMA is cleaved to a 180 to 200 kDa during apoptosis.
- Gene ID
- 4926
- Pathways
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
-