Tumor Protein p73 antibody (full length)

Catalog No. ABIN7879267

The Mouse Monoclonal anti-Tumor Protein p73 antibody (Clone P73-2531) (ABIN7879267) specifically detects Tumor Protein p73 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Tumor Protein p73 antibody (full length) (ABIN7879267)

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tumor Protein p73 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: P73-2531

Product Details anti-Tumor Protein p73 Antibody

Binding Specificity: full length

Purpose: p73 Antibody

Purification: Protein G affinity chromatography

Immunogen: A recombinant full-length human protein was used as the immunogen for this p73 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the p73 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the p73 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Alternative Name: p73

Background: The p53 gene is a widely studied anti-oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 shares considerable sequence similarity with p73, a gene that maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, p73 does not appear to be activated by DNA damaging agents.

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus