ETS2 antibody (full length)

Catalog No. ABIN7879296

The Mouse Monoclonal anti-ETS2 antibody is suitable to detect ETS2 in samples from Human. It has been validated for ELISA, IF and FACS.

Quick Overview for ETS2 antibody (full length) (ABIN7879296)

Target: ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ETS2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-ETS2-1D9

Product Details anti-ETS2 Antibody

Binding Specificity: full length

Purpose: ETS2 Antibody / C-ets-2

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human ETS2 protein was used as the immunogen for the ETS2 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the ETS2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ETS2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ETS2

Target: ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))

Alternative Name: ETS2

Background: ETS2 (Protein C-ets-2) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. ETS2 was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. ETS2 protein expression is complex and changes throughout development. ETS2 appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.

UniProt: P15036

Pathways: EGFR Signaling Pathway, Myometrial Relaxation and Contraction