The Mouse Monoclonal anti-YBX1 antibody (Clone rYBX1-2430) (ABIN7879330) specifically detects YBX1 in IHC (p).
The antibody is reactive with Human samples.
Optimal dilution of the recombinant YB-1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.2 mg/mL
Buffer
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store the recombinant YB-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
YBX1
(Y Box Binding Protein 1 (YBX1))
Alternative Name
YB-1
Background
Y-box binding protein-1 (YBX1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus, YBX1 protein orchestrates transcription of proliferation-related genes, whereas in the cytoplasm it associates with mRNA and directs translation. In human tumor entities, such as breast, lung and prostate cancer, cellular YBX1 expression indicates poor clinical outcome, suggesting that YBX1 is an attractive marker to predict patients' prognosis.