ZHX3 antibody (full length)

Catalog No. ABIN7879380

The Mouse Monoclonal anti-ZHX3 antibody is suitable to detect ZHX3 in samples from Human. It has been validated for WB, ELISA, IF, IHC (p) and FACS.

Quick Overview for ZHX3 antibody (full length) (ABIN7879380)

Target: ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZHX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: PCRP-ZHX3-1G3

Product Details anti-ZHX3 Antibody

Binding Specificity: full length

Purpose: ZHX3 Antibody

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human ZHX3 protein was used as the immunogen for the ZHX3 antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the ZHX3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ZHX3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ZHX3

Target: ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))

Alternative Name: ZHX3

Background: Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).

UniProt: Q9H4I2