ZHX3 antibody (full length)

Catalog No. ABIN7879381

The Mouse Monoclonal anti-ZHX3 antibody (Clone PCRP-ZHX3-1D11) (ABIN7879381) specifically detects ZHX3 in WB, ELISA, IP and FACS. The antibody is reactive with Human samples.

Quick Overview for ZHX3 antibody (full length) (ABIN7879381)

Target: ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZHX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)

Grade: Carrier-free

Clone: PCRP-ZHX3-1D11

Product Details anti-ZHX3 Antibody

Binding Specificity: full length

Purpose: ZHX3 Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human ZHX3 protein was used as the immunogen for the ZHX3 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the ZHX3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the ZHX3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ZHX3

Target: ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))

Alternative Name: ZHX3

Background: Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).

UniProt: Q9H4I2