Recombinant RBP-1 Antibody / Retinol Binding Protein 1
Purification
Protein G affinity chromatography
Immunogen
A recombinant full-length human protein was used as the immunogen for this recombinant RBP-1 antibody. This mAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment).
RBP1
Reactivity: Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal dilution of the recombinant RBP-1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.2 mg/mL
Buffer
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store the recombinant RBP-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
RBP1
(Retinol Binding Protein 1, Cellular (RBP1))
Alternative Name
RBP-1
Background
Retinol Binding Protein 1 or Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. RBP1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.