Recombinant FTL antibody (full length, Light Chain)

Catalog No. ABIN7879406

This Mouse Monoclonal antibody specifically detects FTL in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant FTL antibody (full length, Light Chain) (ABIN7879406)

Target: FTL (Ferritin, Light Polypeptide (FTL))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FTL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RFTL-1386

Product Details anti-FTL Antibody

Binding Specificity: full length, Light Chain

Purpose: Recombinant FTL Antibody / Ferritin Light Chain

Purification: Protein G affinity chromatography

Immunogen: Recombinant full-length human FTL protein was used as the immunogen for the recombinant FTL antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant FTL antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant FTL antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Alternative Name: FTL

Background: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis