Recombinant Ferritin antibody (full length, Light Chain)

Catalog No. ABIN7879492

The Rabbit Monoclonal anti-Ferritin antibody (Clone FTL-3872R) (ABIN7879492) specifically detects Ferritin in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant Ferritin antibody (full length, Light Chain) (ABIN7879492)

Target: Ferritin (FE)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Ferritin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FTL-3872R

Product Details anti-Ferritin Antibody

Binding Specificity: full length, Light Chain

Purpose: Recombinant Ferritin Light Chain Antibody / FTL

Purification: Protein A affinity chromatography

Immunogen: Recombinant full-length human FTL protein was used as the immunogen for the recombinant Ferritin Light Chain antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant Ferritin Light Chain antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Ferritin Light Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Ferritin

Target: Ferritin (FE)

Alternative Name: Ferritin

Background: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis