pan Keratin antibody (pan) (PE)

Catalog No. ABIN7879688

This Mouse Monoclonal antibody specifically detects pan Keratin in IF and FACS. It exhibits reactivity toward Human.

Quick Overview for pan Keratin antibody (pan) (PE) (ABIN7879688)

Target: pan Keratin (panKRT)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This pan Keratin antibody is conjugated to PE

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: SPM115-SPM116

Product Details anti-pan Keratin Antibody (PE)

Binding Specificity: pan

Purpose: Pan Cytokeratin Antibody (PE Conjugate)

Purification: Protein A/G affinity

Immunogen: Human epidermal keratin was used as the immunogen for the Pan Cytokeratin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the PE-conjugated Pan Cytokeratin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the PE-conjugated Pan Cytokeratin antibody in the dark at 2-8oC (do not freeze, conjugate is light sensitive).

Target Details for pan Keratin

Target: pan Keratin (panKRT)

Alternative Name: Pan Cytokeratin

Background: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. This MAb is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.

UniProt: Q7Z794