LYN antibody (pTyr396)

Catalog No. ABIN7879833

The Rabbit Monoclonal anti-LYN antibody is suitable to detect LYN in samples from Human. It has been validated for WB.

Quick Overview for LYN antibody (pTyr396) (ABIN7879833)

Target: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This LYN antibody is un-conjugated

Application: Western Blotting (WB)

Clone: IFI-12

Product Details anti-LYN Antibody

Binding Specificity: pTyr396

Purpose: Phospho-Lyn Antibody (pY396)

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Lyn (surrounding phosphorylated Y396) was used as the immunogen for the phospho-Lyn antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the phospho-Lyn antibody (pY396) should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the phospho-Lyn antibody (pY396) at -20oC.

Target Details for LYN

Target: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Alternative Name: Lyn

Background: Tyrosine-protein kinase Lyn is a non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. [UniProt]

UniProt: P07948

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling, Integrin Complex, BCR Signaling