Recombinant CBL antibody (pTyr774)

Catalog No. ABIN7879839

The Rabbit Monoclonal anti-CBL antibody is suitable to detect CBL in samples from Human. It has been validated for WB.

Quick Overview for Recombinant CBL antibody (pTyr774) (ABIN7879839)

Target: CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CBL antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 28C29

Product Details anti-CBL Antibody

Binding Specificity: pTyr774

Purpose: Phospho-CBL Antibody (pY774)

Purification: Affinity chromatography

Immunogen: A synthetic peptide derived from the area surrounding phosphorylated tyrosine 774 of human CBL was used as the immunogen for the Phospho-CBL antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Phospho-CBL antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Phospho-CBL antibody at -20oC.

Target Details for CBL

Target: CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

Alternative Name: CBL

Background: Casitas B-lineage lymphoma proto-oncogene / CBL is an adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. [UniProt]

UniProt: P22681

Pathways: TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals