ADIPOQ antibody
Quick Overview for ADIPOQ antibody (ABIN7879898)
Target
See all ADIPOQ AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Purpose
- Adiponectin Antibody (azide and preservative free)
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Purification
- Protein G affinity chromatography
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Immunogen
- A synthetic peptide corresponding to the tail region of the Adiponectin molecule was used as the immunogen for the Adiponectin antibody.
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Isotype
- IgG1
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Application Notes
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Optimal dilution of the Adiponectin antibody should be determined by the researcher.
*The ADPN/4256 mAb can also used in a combination ELISA with clone < a href=../tds/adiponectin-antibody-adpn-4255-v8691>ADPN/4255, acting as the capture antibody. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store the Adiponectin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- ADIPOQ (Adiponectin (ADIPOQ))
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Alternative Name
- Adiponectin
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Background
- This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore, adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism. Clone ADPN/4256 is used to detect plasma adiponectin concentrations.
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UniProt
- Q15848
Target
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