ADIPOQ antibody

Catalog No. ABIN7879901

This Mouse Monoclonal antibody specifically detects ADIPOQ in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ADIPOQ antibody (ABIN7879901)

Target: ADIPOQ (Adiponectin (ADIPOQ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADIPOQ antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: ADPN-4255

Product Details anti-ADIPOQ Antibody

Purpose: Adiponectin Antibody

Purification: Protein G affinity chromatography

Immunogen: A synthetic peptide corresponding to the globular head region of the Adiponectin molecule was used as the immunogen for the Adiponectin antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the Adiponectin antibody should be determined by the researcher.

*The ADPN/4255 mAb can be used in a combination ELISA with clone < a href=../tds/adiponectin-antibody-adpn-4256-v8692>ADPN/4256, acting as the detection antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Adiponectin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for ADIPOQ

Target: ADIPOQ (Adiponectin (ADIPOQ))

Alternative Name: Adiponectin

Background: This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore, adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism. (Hotta K, et al.)

UniProt: Q15848