ALAS1 antibody

Catalog No. ABIN7879963

The Rabbit Monoclonal anti-ALAS1 antibody (Clone EOA-1) (ABIN7879963) specifically detects ALAS1 in WB, IF and ICC. The antibody is reactive with Human samples.

Quick Overview for ALAS1 antibody (ABIN7879963)

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ALAS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: EOA-1

Product Details anti-ALAS1 Antibody

Purpose: ALAS1 Antibody / 5'-Aminolevulinate synthase 1

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human ALAS1 was used as the immunogen for the ALAS1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ALAS1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the ALAS1 antibody at -20oC.

Target Details for ALAS1

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Alternative Name: ALAS1

Background: The ALAS1 gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate.

UniProt: P13196

Pathways: Regulation of Lipid Metabolism by PPARalpha