Recombinant Annexin VII antibody

Catalog No. ABIN7879982

This Rabbit Monoclonal antibody specifically detects Annexin VII in WB, IHC, IF, ICC and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Recombinant Annexin VII antibody (ABIN7879982)

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Annexin VII antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 30A51

Product Details anti-Annexin VII Antibody

Purpose: ANXA7 Antibody / Annexin A7

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Annexin A7 was used as the immunogen for the ANXA7 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ANXA7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the ANXA7 antibody at -20oC.

Target Details for Annexin VII

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Alternative Name: ANXA7

Background: ANXA7 antibody detects annexin A7, a calcium and phospholipid binding protein encoded by the ANXA7 gene. Annexin A7 belongs to the annexin family of proteins characterized by conserved annexin repeats that mediate calcium dependent membrane interactions. ANXA7 functions in membrane fusion, exocytosis, and calcium signaling, making it an important regulator of vesicular transport and cellular communication.

ANXA7 antibody is widely applied in neuroscience, cardiovascular biology, and oncology. In neurons, annexin A7 regulates synaptic vesicle exocytosis and neurotransmitter release. In cardiac tissue, it contributes to calcium handling and contractility. Altered expression of ANXA7 has been observed in several cancers, where it influences tumor growth, invasion, and therapy resistance. By detecting annexin A7, researchers can study its diverse roles across tissues and disease contexts.

In western blot assays, ANXA7 antibody detects protein bands of expected molecular weight across tissue lysates. Immunohistochemistry highlights localization in brain, heart, and epithelial tissues. Immunofluorescence provides high resolution mapping of annexin A7 distribution at cellular membranes and vesicular compartments.

Annexin A7 participates in calcium dependent signaling cascades and contributes to regulation of phospholipase activity. It plays a role in membrane repair, cell proliferation, and apoptosis. Dysregulation of ANXA7 expression has been implicated in tumorigenesis, cardiovascular dysfunction, and neurological disease. By using ANXA7 antibody, scientists can explore how annexin mediated signaling influences both health and pathology.

ANXA7 antibody from NSJ Bioreagents provides dependable specificity for studying annexin biology, vesicle trafficking, and calcium signaling. Its proven performance across applications supports accurate detection of annexin A7 in both experimental and clinical research contexts.

UniProt: P20073