APOBEC3B antibody

Catalog No. ABIN7879989

The Rabbit Polyclonal anti-APOBEC3B antibody is suitable to detect APOBEC3B in samples from Human. It has been validated for WB.

Quick Overview for APOBEC3B antibody (ABIN7879989)

Target: APOBEC3B (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOBEC3B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APOBEC3B Antibody

Purpose: APOBEC3B Antibody / A3B

Sequence: FNNDPLVLRR RQTYLCYEVE R

Purification: Antigen affinity purified

Immunogen: Amino acids FNNDPLVLRRRQTYLCYEVER were used as the immunogen for the APOBEC3B antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the APOBEC3B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the APOBEC3B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for APOBEC3B

Target: APOBEC3B (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B))

Alternative Name: APOBEC3B

Background: Probable DNA dC->dU-editing enzyme APOBEC-3B is a protein that in humans is encoded by the APOBEC3B gene. This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9UH17